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目的:分析在对宫颈持续性高危型人乳头状瘤病毒(HPV)感染患者实施治疗时,采用保妇康栓联合中药的治疗效果和治疗安全性。方法:随机收集本院在2013年10月至2015年10月收治的200例宫颈持续性高危型HPV感染患者,使用随机数字表法将其分为观察组和对照组,各100例。对照组患者使用保妇康栓治疗,观察组患者在对照组基础上实施中药治疗,比较两组患者的疗效。结果:观察组患者治疗后显效率以及总有效率均明显高于对照组,差异具有统计学意义(P<0.05)。两组患者并发症发生率比较,差异均无统计学意义(P>0.05)。结论:对宫颈持续性高危型HPV感染患者进行治疗,在保妇康栓的基础上实施中药治疗,能够明显提升临床治疗效果,同时在安全性上两者之间并无较大差异,宫颈上皮细胞中E6、E7蛋白指标也基本恢复正常。
Objective: To analyze the therapeutic effect and treatment safety of Baofukang suppository combined with traditional Chinese medicine (TCM) in the treatment of patients with persistent high-risk cervical HPV infection. Methods: A total of 200 consecutive patients with high-risk HPV infection who were treated in our hospital from October 2013 to October 2015 were randomly divided into observation group and control group with 100 cases in each group. Patients in the control group were treated with Baofukang suppository. Patients in the observation group were treated with traditional Chinese medicine on the basis of the control group, and the curative effect was compared between the two groups. Results: The effective rate and total effective rate of observation group were significantly higher than that of control group, the difference was statistically significant (P <0.05). There was no significant difference in the complication rates between the two groups (P> 0.05). Conclusion: The treatment of patients with persistent high-risk HPV infection in the cervix, the implementation of traditional Chinese medicine on the basis of Baofukang suppository, can significantly improve the clinical treatment effect, while no significant difference in safety between the two, cervical epithelium Cell E6, E7 protein index also returned to normal.