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目的:研究脑复灵对小鼠心脑缺血的保护作用。方法:采用小鼠断颅、结扎双侧颈总动脉、空气栓、利多卡因中毒等方法。结果:脑复灵能明显延长断颅小鼠的喘息时间,延长结扎双侧颈总动脉而致脑缺血小鼠的存活时间。对空气栓而致的小鼠心脑缺血有明显的保护作用;并能延长利多卡因中毒小鼠的存活时间。结论:提示脑复灵有抗心脑缺血的作用。
Objective: To study the protective effect of naofitrine on heart and brain ischemia in mice. Methods: The mice were divided into two groups: cranial craniotomy, bilateral common carotid artery ligation, air suppository and lidocaine poisoning. RESULTS: Nevofosin significantly prolonged the wheezing time of severed mice and prolonged the survival time of cerebral ischemic mice caused by ligation of both common carotid arteries. It has obvious protective effect on mouse heart-cerebral ischemia caused by air embolism, and it can prolong the survival time of mice with lidocaine poisoning. Conclusion: It is suggested that the cerebral follicles have anti-cardio-cerebral ischemia effects.