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氟中毒可损伤机体的多种器官。为了探讨氟中毒对机体循环系统的影响,以大鼠作为动物实验模型,以血流动力学的一些参数作为研究指标,对大鼠进行了实验性的慢性高氟染毒实验。1材料与方法1.1氟化钠溶液配制选用分析纯氟化钠(Na F),购自北京化工厂,应用蒸馏水配置成150 mg/L氟化钠熔液。1.2实验动物选取Wistar大鼠30只,其体重为180~220 g,由福建医科大学实验室提供,随机分为对照组以及中
Fluorosis can damage many organs of the body. In order to investigate the effects of fluorosis on circulatory system, rats were used as experimental animal models and some parameters of hemodynamics were used as experimental indexes to conduct experimental chronic high fluorine exposure in rats. 1 Materials and methods 1.1 Preparation of sodium fluoride solution selection Analysis of pure sodium fluoride (Na F), purchased from Beijing Chemical Plant, the application of distilled water to 150 mg / L sodium fluoride melt. 1.2 Experimental animal Wistar rats selected 30, weighing 180 ~ 220 g, provided by the Fujian Medical University Laboratory, were randomly divided into control group and in