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白斑(IeukopIakia)发生在口腔粘膜的角化性白色斑块状损害,主要的病理改变是粘膜上皮的角化不良或有上皮的非典型增生改变。由于白斑的上皮层增厚和发生过度角化,临床表现白色斑块状病损较周围正常粘膜稍隆起,舌舐有粗涩感,不易被擦拭除去。 口腔白斑的发病率,Waldrom等报告为6.2%,许氏报告为8%。性别上男性发病明显高于女性,并随着年龄的增长发病
Leukoplakia (Ieukop Iakia) occurs in the keratinized, white plaque-like lesions of the oral mucosa. The main pathological changes are dyskeratosis of the epithelium of the mucous membranes or alteration of the dysplasia of the epithelium. Due to thickening of the epithelial layer of the leukoplakia and hyperkeratosis, the clinical manifestations of white plaque-like lesions are slightly elevated compared to the surrounding normal mucosa, and the tongue and palate have a coarse and astringent sensation and are not easily removed by rubbing. The incidence of oral leukoplakia was reported by Waldrom et al. 6.2% and Hsu reported 8%. Gender is significantly higher in males than females and occurs with age