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目的探讨分析老年人频繁再发性尿路感染的危险因素。方法 83例尿路感染老年患者,根据是否频繁再发分为频繁再发性尿路感染组(46例)和非频繁再发性尿路感染组(37例)。观察尿培养结果 ,并分析两组患者的临床资料及频繁再发性尿路感染的高危因素,包括空腹血糖、糖化血红蛋白、血清白蛋白、C反应蛋白、超广谱β-内酰胺酶(ESBLs)、结石、前列腺增生、膀胱颈硬化、卧床、留置尿管等。结果尿培养中,大肠杆菌67例,肺炎克雷白杆菌2例,白色念珠菌3例,摩根氏摩根菌3例,奇异变形杆菌2例,草绿色链球菌、枸橼酸杆菌、氟劳地氏枸橼酸杆菌、粪球菌、产气肠杆菌、施氏假单胞菌各1例。两组患者的年龄、糖化血红蛋白、空腹血糖、血清白蛋白、C反应蛋白比较差异均无统计学意义(P>0.05)。两组患者的糖尿病、结石、前列腺增生、膀胱颈硬化、卧床、留置尿管情况比较差异无统计学意义(P>0.05);两组患者的尿潴留、ESBLs情况比较差异具有统计学意义(P<0.05)。经二元Logistic回归方程分析显示,尿潴留、ESBLs情况是老年人频繁再发性尿路感染的高危因素。结论频繁再发性尿路感染的高危因素为尿潴留和ESBLs。
Objective To explore the risk factors for frequent recurrent urinary tract infection in the elderly. Methods Eighty-three elderly patients with urinary tract infection were divided into two groups according to whether they were recurrent or recurrent urinary tract infection (n = 46) or non-recurrent urinary tract infection (n = 37). The urinary culture results were observed and the clinical data and the risk factors for frequent recurrent urinary tract infection were analyzed in two groups, including fasting blood glucose, glycosylated hemoglobin, serum albumin, C-reactive protein, ESBLs ), Stones, benign prostatic hyperplasia, bladder neck sclerosis, bed rest, catheter indwelling. Results In urine culture, 67 cases of Escherichia coli, 2 cases of Klebsiella pneumoniae, 3 cases of Candida albicans, 3 cases of Morganella morganii, 2 cases of Proteus mirabilis, Streptococcus viridans, Citrobacter, Citrobacter, fecal bacteria, Enterobacter aerogenes, Pseudomonas stutzer in 1 case. There was no significant difference in age, HbAlc, fasting blood glucose, serum albumin and C-reactive protein between the two groups (P> 0.05). The two groups of patients with diabetes, stones, benign prostatic hyperplasia, bladder neck sclerosis, bed rest, indwelling catheter conditions were no significant difference (P> 0.05); two groups of patients with urinary retention, ESBLs difference was statistically significant (P <0.05). Logistic regression analysis showed that urinary retention and ESBLs were risk factors for frequent recurrent urinary tract infections in the elderly. Conclusions High risk factors for frequent recurrent urinary tract infections are urinary retention and ESBLs.