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建立了用离子对高效液相色谱法，不经溶剂提取，直接定量测定血浆中原型无环鸟苷的方法。该法高、中、低浓度的平均回收率为95．83％，RSD=0．85（n=18），方法精密度为：RSD=0．93（n=6）。该法具有灵敏、准确、简便、快速的特点。
A method for direct determination of arginine in plasma by ion-pair high performance liquid chromatography without solvent extraction was established. The average recoveries of high, medium and low concentrations were 95.83%, RSD = 0.85 (n = 18). The precision of the method was: RSD = 0.93 (n = 6). The method is sensitive, accurate, simple and fast.