多巴胺受体激动剂能改善左旋多巴治疗帕金森病患者时所产生的波动现象。在未治疗过的病人中,应用激动剂药物既可缓介临床症状又能避免长期用药的副作用,而且低剂量多巴胺能激动剂即可取得疗效。本文作者报导一组未曾用过左旋多巴或多巴胺能激动剂治疗的帕 Dopamine receptor agonists improve fluctuations in levodopa in patients with Parkinson’s disease. In untreated patients, the use of agonist drugs can both ameliorate clinical symptoms and avoid the side effects of long-term medication, and low doses of dopaminergic agonists can be effective. The authors report that a group of patients who have not been treated with levodopa or dopaminergic agonists