论文部分内容阅读
目的探讨青春期肥胖儿童血压与体质指数(BMI)及空腹血清胰岛素(INS)的关系。方法选取13～14岁青春期肥胖儿童65名和体重正常儿童87名为研究对象,测量身高、体重、血压,并计算BMI,用放免法测定空腹血清INS。结果青春期肥胖组儿童高血压发生率(26.15%)明显高于对照组儿童(2.35%)(P=0.000),肥胖组高血压发生的相对危险度为11.377;肥胖组儿童空腹血清INS平均为(26.87±11.57)mU/L,高于对照组儿童(16.34±5.28)mU/L(P=0.000);收缩压(SBP)和舒张压(DBP)与空腹血清INS在控制BMI后均无相关性(P<0.05);SBP和DBP与BMI在控制INS后仍显示存在正相关关系(P<0.05)。结论肥胖儿童发生高血压的危险性明显高于体重正常儿童;肥胖儿童高血压的发生与BMI呈正相关,与血清INS水平变化无关。
Objective To investigate the relationship between blood pressure and body mass index (BMI) and fasting serum insulin (INS) in adolescent obese children. Methods Totally 65 obese adolescents aged 13-14 years and 87 normal weight children were enrolled in this study. Height, weight, blood pressure were measured and BMI was calculated. Insulin fasting serum was determined by radioimmunoassay. Results The incidence of hypertension in adolescent obesity group was significantly higher than that in control group (26.15%) (P = 0.000). The relative risk of hypertension in obesity group was 11.377. The average fasting serum INS in obesity group was ( 26.87 ± 11.57) mU / L, higher than that of control group (16.34 ± 5.28) mU / L (P = 0.000); SBP and DBP had no correlation with fasting serum INS after controlling BMI (P <0.05). There was a positive correlation between SBP, DBP and BMI after controlling INS (P <0.05). Conclusions The risk of developing hypertension in obese children is significantly higher than that in normal weight children. The incidence of hypertension in obese children is positively correlated with BMI, but not with the change of serum INS level.