论文部分内容阅读
目的:评价西帕依固龈液预防及治疗放射性口腔粘膜炎的临床疗效。方法:108(例)鼻咽癌放射治疗患者随机分为2组,实验组58例用西帕依固龈液含漱,对照组50例用氯乙定含漱剂(口泰)进行治疗。观察放射性口腔粘膜炎的发生时间和程度。结果:实验组的Ⅰ级放射性口腔粘膜炎发生的时间推迟4～5 d。与对照组相比,实验组Ⅲ级放射性口腔粘膜炎的发生率明显减少(P<0.01),实验组未出现Ⅳ级放射性口腔粘膜炎,与对照组相比差异有统计学意义(P<0.05)。结论:西帕依固龈液作为一种治疗口腔粘膜炎的口腔用药,可以推迟放射性口腔粘膜炎的发生时间,减轻放射性口腔粘膜的损伤。
OBJECTIVE: To evaluate the clinical efficacy of Xipayi gingival fluid in the prevention and treatment of radiation-induced oral mucositis. METHODS: One hundred and eighty patients with nasopharyngeal carcinoma were randomly divided into two groups. 58 cases in the experimental group were treated with Xipayi mouth rinse solution, while 50 cases in the control group were treated with Cloridine (Routine). Observe the time and extent of radiation oral mucositis. Results: The grade Ⅰ radioactive oral mucositis in the experimental group was delayed 4 to 5 days. Compared with the control group, the incidence of grade Ⅲ radioactive oral mucositis was significantly decreased in the experimental group (P <0.01), but there was no grade Ⅳ radiation-induced oral mucositis in the experimental group compared with the control group (P <0.05 ). CONCLUSIONS: Sipayi gingival fluid as an oral treatment for oral mucositis can delay the onset of radiation-induced oral mucositis and reduce the damage of radioactive oral mucosa.