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探讨豆奶与铁、锌和／或维生素Ｃ强化豆奶（营养豆奶）改善学习记忆的功能。方法：选用初断乳小 鼠，喂饲豆奶或营养豆奶４周，进行水迷宫试验、跳台试验、避暗试验；并于试验不同阶段分别测定小鼠体重、血红 蛋白和血清铁。结果：①各试验组小鼠前２周体重增加值、血红蛋白增加值及血清铁值与对照组相比，均有增高趋 势，并以Ｆｅ＋Ｚｎ组及Ｆｅ＋Ｚｎ＋Ｖｃ组较明显；②水迷宫试验中，Ｆｅ＋Ｚｎ组及Ｆｅ＋Ｚｎ＋Ｖｃ组小鼠重测验时错误次数均显著低 于对照组（Ｐ＜０．０５， Ｐ＜０．０１）； Ｆｅ＋Ｚｎ＋Ｖｃ组训练及重测验时达标所需次数均显著少于对照组（Ｐ＜０．０５，Ｐ＜０．００２）； ③跳台试验中，各试验组重测验潜伏期均显著长于对照组（分别为Ｐ＜０．０５， ＜０．００１， Ｐ＜０．０１， Ｐ＜０．０５）；④避暗 试验中， Ｆｅ＋Ｚｎ组重测验时５ｍｉｎ内错误次数显著低于对照组（Ｐ＜０．０５）； Ｆｅ＋Ｚｎ＋Ｖｃ组训练及重测验潜伏期均显著短于 对照组 （Ｐ＜０．０５， Ｐ＜０．０１）．结论：豆奶、铁锌及铁锌维生素Ｃ强化豆奶均可促进初断乳小鼠的体格发育；铁锌及 铁锌维生素Ｃ强化豆奶还可能具有改善试验小鼠学习记忆能力的作用。
To explore the function of soy milk and iron, zinc and / or vitamin C fortified soy milk (nutrition soy milk) to improve learning and memory. Methods: Weaned mice were fed with soymilk or nutrition soy milk for 4 weeks. Water maze test, step-down test and dark-avoidance test were performed. Body weight, hemoglobin and serum iron were measured at different stages of the experiment. Results: (1) The body weight gain, hemoglobin increase value and serum iron value in the first 2 weeks of each experimental group increased compared with the control group, and were more obvious in Fe + Zn group and Fe + Zn + Vc group. ② In the water maze test, Fe + Zn (P <0.05, P <0.01). The number of times required to reach the goal of training and retest in Fe + Zn + Vc group was significantly less than that in control group (P <0.05, P <0.01) <0.05, P <0.002). ③ In the step-down test, the retest latency of each test group was significantly longer than that of the control group (P <0.05, <0.001, P < (P <0.05). ④ In the dark-avoidance test, the number of errors in the Fe + Zn group during retesting was significantly lower than that in the control group within 5 minutes (P <0.05), and the training and retest latency in Fe + Zn + Vc group was significantly shorter than that in the control group .05, P <0.01). Conclusion: Soy milk, iron-zinc and iron-zinc-vitamin C fortified soy milk can promote the physical development of weaned mice. Iron-zinc and zinc-zinc vitamin C fortified soy milk may also play an important role in improving learning and memory in mice.