据有关文献报告,内源性吗啡样物质和吗啡可影响垂体后叶激素的释放,在下丘脑、神经垂体以及其它神经组织中,内啡肽与加压素常共同存在并互相影响。为进一步探讨垂体后叶素与吗啡镇痛的关系,我们采用扭体法和热板法,观察了脑内注射垂体后叶素后,小剂量吗啡对小自鼠的镇痛作用。 一、扭体法:小白鼠雌雄不限,体重20—25g,实验前未用任何药物。将其随机分成三组,甲乙两组腹腔注射常用镇痛剂量 According to the literature, endogenous morphine-like substances and morphine can affect the release of pituitary hormones in the hypothalamus, neurohypophysis and other nervous tissues, endorphins and vasopressin often coexist and affect each other. To further explore the relationship between vasopressin and morphine analgesia, we used writhing and hot plate method to observe the analgesic effect of morphine on mice after injection of pituitrin. First, writhing: mice male or female, weight 20-25g, before the experiment without any drugs. They were randomly divided into three groups, A and B two groups commonly used intraperitoneal injection of analgesic dose