关于成人呼吸窘迫综合征(ARDS)的病理生理机理,近年特别强调补体和粒细胞的相互作用。急性创伤和革兰氏阴性菌败血症可激活补体系统,增加粒细胞粘附,导致肺部微血管内白细胞郁滞,产生肺功能不全,后者的发生机理不清楚,可能由于被激活的粒细胞释放组织破坏性物质所致。作者在有ARDS危险的病人中连续测定血中两种特殊的颗粒蛋白质,乳铁蛋白 With regard to the pathophysiology of adult respiratory distress syndrome (ARDS), in recent years special emphasis has been placed on the interaction of complement and granulocyte. Acute trauma and Gram-negative sepsis can activate the complement system, increase granulocyte adhesion, lead to leukocyte accumulation in the lung microvasculature, resulting in pulmonary insufficiency, the latter mechanism is not clear, probably due to the release of activated granulocytes Organized by destructive substances. The authors in two patients at risk of ARDS continuous determination of blood two special particulate protein, lactoferrin