研究结果表明:①氯醚避孕针长期使用对家兔体重增长无影响。②各组动物实验前后血常规检查,结果均在正常值范围内,未见外周血中白细胞总数及其分类的异常改变。③各项生化指标检查,可见给药组血清GPT活性在9个月以内有升高(P<0.01),但随继续用药逐渐恢复正常,肝脏排泄机能、肾功能及血糖、血清蛋白、血脂等无明显影响。④各组动物尿常规检查未见异常改变。以上结果提示,长效氯醚避孕针长期应用,对家兔重要器官的机能无明显毒性作用。 The results show that: ① long-term use of chlorine ether contraceptive rabbits weight gain no effect. ② Before and after the blood tests in all groups of animals, the results were within the normal range, no abnormal changes in the total number of leukocytes in the peripheral blood and its classification. (3) The biochemical tests showed that the serum GPT activity of the administration group increased within 9 months (P <0.01), but gradually returned to normal with continuous administration, hepatic excretion function, renal function, blood glucose, serum albumin, blood lipid, etc. No significant effect. ④ no abnormal changes in urine routine examination in all groups of animals. The above results suggest that the long-acting application of long-acting chloroether contraception has no obvious toxic effect on the function of important organs of rabbits.