论文部分内容阅读
鉴于目前临床上常用的抗癌药物大多属抗代谢物,对正常细胞具有毒性作用,近年提出了新的课题——营养疗法。已有一些工作指出,维生素 A 与 E 具有延缓细胞衰老、防止癌变的效能。最近,美国 Ohio 州 Merchurst学院圣 Thomos 研究所的 M.E.Poydock 等报道,用维素生 C 和 B_(12)混合液处理小鼠腹水型移植瘤:S37肉瘤、Krebs-2、艾氏瘤以及 L1210白血病细胞等,能明显地抑制这些瘤细胞的分裂,且对正常细胞无毒性作用。体外温育试验表明,经处理后的瘤细胞的分裂指数下降至另,而非恶性的 L929系细胞乃显示活跃的分裂行为。体内
In view of the fact that most commonly used anti-cancer drugs in the clinic are anti-metabolites and have toxic effects on normal cells, a new topic has been proposed in recent years: nutritional therapy. Some work has pointed out that vitamins A and E have the effect of delaying cell aging and preventing canceration. Recently, MEPoydock et al. (St. Thomas Research Institute, Merchurst College, Ohio, USA) reported that mouse ascites type transplanted tumors were treated with a mixed solution of vemuracin C and B_(12): S37 sarcoma, Krebs-2, Alzheimer’s tumor, and L1210 leukemia. Cells, etc., can significantly inhibit the division of these tumor cells and have no toxic effects on normal cells. The in vitro incubation test showed that the mitotic index of the treated tumor cells decreased to another, whereas the non-malignant L929-based cells showed active divisional behavior. in vivo