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目的:观察桂枝茯苓汤合二陈汤联合西药治疗多囊卵巢综合征(PCOS)的效果。方法:选取84例PCOS患者作为研究对象,采用随机数字表法将患者分为对照组和观察组各42例,对照组予以达英-35口服,观察组在对照组治疗基础上予以桂枝茯苓汤合二陈汤,行中医症状评分,观察2组治疗前后睾酮(T)、促卵泡生成素(FSH)、黄体生成素(LH)、卵泡体积的变化情况和服药后的不良用药反应,随访6月了解2组的排卵率和妊娠率。结果:治疗3月,2组T、FSH、LH、卵泡体积与治疗前相比,差异均有统计学意义(P<0.05);观察组T、LH、卵泡体积与对照组比较,差异均有统计学意义(P<0.05)。观察组带下量多、身重不爽、神疲乏力、腹胀评分均低于对照组,差异均有统计学意义(P<0.05)。观察组排卵率和妊娠率分别为85.71%、35.29%,均高于对照组(P<0.05)。结论:桂枝茯苓汤合二陈汤联合西药治疗PCOS,能够有效改善症状,调整性激素水平,促排卵,提高妊娠率。
Objective: To observe the effect of Guizhi Fuling Decoction and Erchen Decoction combined with western medicine in treating polycystic ovary syndrome (PCOS). Methods: Eighty-four patients with PCOS were enrolled in this study. The patients were divided into control group and observation group by random number table method, 42 cases in each group. The control group was treated with Ying-35 orally. The observation group was treated with Guizhi Fuling Decoction of Tang and Erchen soup was performed. The symptoms of TCM were evaluated. The changes of testosterone (T), follicle stimulating hormone (FSH), luteinizing hormone (LH) and follicular volume before and after treatment were observed and the adverse reactions were observed after treatment June to understand the two groups of ovulation and pregnancy rates. Results: The levels of T, FSH, LH and follicle in the two groups were significantly different from those before treatment (P <0.05). The difference of T, LH and follicular volume between the two groups were statistically significant Statistical significance (P <0.05). The observation group with more belly, unwell, fatigue, abdominal distension scores were lower than the control group, the difference was statistically significant (P <0.05). The observation group ovulation rate and pregnancy rate were 85.71%, 35.29%, were higher than the control group (P <0.05). Conclusion: Guizhi Fuling Decoction combined with Erchen Decoction combined with Western medicine in treating PCOS can effectively improve the symptoms, regulate the level of sex hormones, promote ovulation and improve the pregnancy rate.