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作者用竞争性蛋白结合法测定家兔血小板悬浮液的cAMP含量,观察到冠心Ⅱ号提取液在抑制ADP诱导血小板聚集的剂量下能使血小板内cAMP含量明显增加,此作用与前列腺素E_1有协同作用。推测冠心Ⅱ号的作用环节可能是抑制了血小板磷酸二酯酶.
The authors used competitive protein binding assay rabbit cAMP content of platelet suspension, observed that coronary heart Ⅱ extract at a dose that inhibits ADP-induced platelet aggregation can make platelet cAMP content increased significantly, the role of prostaglandin E_1 Synergy. It is concluded that the role of coronary heart Ⅱ may be part of the inhibition of platelet phosphodiesterase.