论文部分内容阅读
目的观察中西医结合治疗前列腺增生症(BPH)的临床效果。方法将124例BPH患者按数字表法随机分为观察组和对照组,每组62例,两组患者均给予心理疏导、起居养生指导和口服非那雄胺、盐酸坦索罗辛药物治疗,观察组同时加服中药六味地黄丸,两组疗程均为3个月。观察两组临床疗效,比较两组国际前列腺症状评分(I-PSS)、生活质量评分(QOL)、前列腺体积(PV)、最大尿流量(MFR)、残余尿量(PVR)指标变化、不良反应发生率及随访6个月病情复发率。结果观察组总有效率达95.2%,明显高于对照组的83.9%(P<0.05);观察组治疗后I-PSS、QOL、PV、MFR、PVR指标改善程度明显优于对照组(P均<0.01),不良反应发生率和随访6个月病情复发率均明显小于对照组(P均<0.05)。结论中西医结合治疗BPH比单纯西医治疗可获得更为满意的治疗效果,更能明显缓解临床症状和提高生存质量,不失为BPH患者有效的药物治疗方案。
Objective To observe the clinical efficacy of integrated traditional Chinese and western medicine in the treatment of benign prostatic hyperplasia (BPH). Methods A total of 124 patients with BPH were randomly divided into observation group and control group according to the digital table method. There were 62 patients in each group. The patients in both groups were given psychological counseling, daily living regimen and oral finasteride, tamsulosin hydrochloride drug therapy, Observation group also served traditional Chinese medicine Liu Wei Di Huang Wan, two courses of treatment were 3 months. The clinical efficacy of the two groups were observed. The changes of I-PSS, QOL, PV, MFR and PVR were compared between the two groups. Adverse reactions Incidence and follow-up of 6 months disease recurrence rate. Results The total effective rate in observation group was 95.2%, which was significantly higher than that in control group (83.9%, P <0.05). The improvement of I-PSS, QOL, PV, MFR and PVR in observation group was better than that in control group <0.01). The incidence of adverse reactions and recurrence rate at 6 months follow-up were significantly lower than those in the control group (all P <0.05). Conclusion The combination of traditional Chinese and Western medicine treatment of BPH than Western medicine treatment can be more satisfied with the treatment effect, but also significantly relieve clinical symptoms and improve the quality of life, after all, an effective drug treatment of BPH patients.