确定一种治疗糖尿病的药物是否适合应包括一系列因素。有效而安全是最主要的;其次是胃肠道的吸收要完全和有规律,对代谢的控制要有适宜的半寿期和安全的治疗剂量。当然,亦要注意其副作用;对体重的影响;早期低血糖发生率;药物体内积蓄和由此引起的严重低血糖症等。本文介绍一种新的低剂量的磺脲类口服抗糖尿病药物——克糖利,并对该药作一讨论。 Determining whether a drug to treat diabetes is appropriate should include a range of factors. Effective and safe is the most important; followed by the gastrointestinal absorption to be complete and regular, metabolic control should have a suitable half-life and safe therapeutic dose. Of course, we must also pay attention to its side effects; the impact on body weight; the incidence of early hypoglycemia; drug accumulation in the body and the resulting severe hypoglycemia. This article describes a new low-dose sulfonylurea oral antidiabetic drug - grams of sugar, and the drug for a discussion.