抗哮喘药物朱冰，吴若（中国医学科学院药物研究所药理室北京１０００５０）哮喘为可变及可逆的气道阻塞，是因支气管对抗原性或非抗原性刺激反应后引起的气道狭窄。虽然曾强调过气道平滑肌收缩是气道阻塞的主要发病机制，后逐步了解到气道壁水肿导致血管泄漏，血浆渗出物... Anti-asthma drugs ZHU Bing, WU Ruo (Department of Pharmacology, Institute of Materia Medica, Chinese Academy of Medical Sciences, Beijing 100050, China) Asthma is a variable and reversible obstruction of the airway due to bronchial airway stenosis caused by antigenic or non-antigenic stimuli. Although it has been emphasized that the contraction of airway smooth muscle is the main pathogenesis of airway obstruction, we gradually understand that airway wall edema leads to vascular leakage and plasma exudate.