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用实验动物体外寄生虫监测常规方法,观察了螨虫在BALB/c小鼠体外寄生状况。结果显示感染率为14%,寄生螨虫的种类为鼠癣螨(Myocoptesmusculinus),螨虫的寄生部位通常在脸、颈和背部,并将卵产于毛干上。重度感染引起小鼠脱毛,表面皮肤肿胀,皮肤表面变硬和变厚。组织病理切片观察,在显微镜下,一般感染仅引起表皮层增厚。在一只感染严重的小鼠中,皮肤组织发生了较为严重的病理变化,表皮表面形成散在的小脓肿,表皮下层淋巴细胞和成纤维细胞成堆的聚集在一起,并有散在的出血现象,伴随炎细胞的浸润。皮肤肌细胞层无变化。
The parasites in laboratory animals were monitored by routine methods and the parasitic status of mites in BALB / c mice was observed. The results showed that the infection rate was 14%. The species of parasitic mites was Myocoptesmusculinus. The mites’ parasitic sites were usually on the face, neck and back, and the eggs were produced on the hair shaft. Severe infections cause hair removal in mice, swelling of the surface skin, hardening and thickening of the skin surface. Histopathological observation, under the microscope, the general infection caused only the epidermis thickening. In a mouse with severe infection, serious pathological changes have taken place in the skin tissues, scattered small abscesses formed on the surface of the epidermis, and the lower epidermal lymphocytes and fibroblasts accumulate in piles together with scattered bleeding. Accompanied by infiltration of inflammatory cells. No change in skin myocyte layer.