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目的探讨婴幼儿不同分型中耳炎的治疗策略,预防抗生素滥用。方法对该院2015年1月—2016年12月门急诊收治的婴幼儿中耳炎患者1 080例(其中急性中耳炎864例,分泌性中耳炎179例,非渗出性中耳炎26例,咽鼓管功能障碍11例)做回顾性研究。结果 1 080名中耳炎患儿依家长自愿分为血清降钙素原组(PCT组)和经验治疗组(非PCT组),动态检测PCT组抗生素使用时间及使用率均小于非PCT组,差异有统计学意义(P<0.01),而治疗时间和有效率差异无统计学意义(P>0.05)。结论采用降钙素原(PCT)动态检测指导婴幼儿中耳炎治疗可降低抗生素的使用,在取得良好治疗效果的同时,避免抗生素滥用,降低药品花费。
Objective To explore the treatment strategies for different types of otitis media in infants and young children to prevent the abuse of antibiotics. Methods A total of 1 080 cases of otitis media in our hospital from January 2015 to December 2016 were selected, including 864 cases of acute otitis media, 179 cases of secretory otitis media, 26 cases of otitis media with effusion, eustachian tube dysfunction 11 cases) to do a retrospective study. Results 1 080 children with otitis media voluntarily divided into serum procalcitonin group (PCT group) and experience treatment group (non-PCT group) according to their parents voluntarily. The time of using antibiotics and the rate of using antibiotics in PCT group were less than that of non-PCT group (P <0.01), but there was no significant difference between the treatment time and the effective rate (P> 0.05). Conclusions The use of procalcitonin (PCT) dynamic test to guide the treatment of otitis media in infants and young children can reduce the use of antibiotics and achieve good therapeutic effect while avoiding the abuse of antibiotics and reducing the cost of medicines.