一、阿司匹林阿司匹林在临床应用已近百年。过去它一向是作为解热止痛、消炎抗风湿药物广泛应用的。但在临床实践中发现它有明显的副作用(如引起胃痛,甚至导致胃出血),所以逐渐被一些新的药物所替代。然而医务工作者发现:它能抑制环氧酶的活性,减少凝栓质(TA_2)的形成,从而抑制血管收缩及血小板聚集。血管收缩及血小板聚集形成血栓,在人体出血时是一种自然的止血功能。但若发生在心肌、脑的小血管内,就会使管腔闭塞而影响心肌、脑的微循环,这是造成心、脑缺血坏死的主要原因。阿司匹林并能代谢性扩张冠状动脉和脑血管,亦能降低血脂浓度。因 First, aspirin aspirin in clinical use for nearly a century. In the past it has been widely used as antipyretic analgesic, anti-inflammatory antirheumatic drugs. However, it has been found in clinical practice that it has obvious side effects (such as stomach pain and even gastric hemorrhage), so it is gradually replaced by some new drugs. However, medical workers found that: it can inhibit the activity of cyclooxygenase, reducing the formation of coagulation (TA_2), thereby inhibiting vasoconstriction and platelet aggregation. Vasoconstriction and platelet aggregation form thrombus, which is a natural hemostatic function when bleeding in human body. However, if it occurs in the myocardium, the brain of small blood vessels, it will make the lumen occlusion and affect the heart, brain microcirculation, which is caused by heart and brain ischemia and necrosis of the main reasons. Aspirin and metabolic expansion of coronary and cerebral blood vessels, but also reduce blood lipids. because