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由布鲁氏104—M 活菌苗多次复种所致之重致敏反应,在停止该菌苗接种七年之后的观察结果:8例全身性重致敏反应者的菌素反应强度,全部出现加重和发展的趋势,补体结合试验亦保持阳性,且有慢性布鲁氏菌病症状。显然,由布鲁氏菌抗原物质,多次刺激所产生的既有细胞免疫也有体液免疫的这种全身性重致敏反应,是一种免疫性疾病,应引起我们应有的注意和重视。在继续从事畜产品加工工作,接触相应的抗原物质的情况下,多数致敏者出现致敏程度增强的现象,而在脱离接触相应的抗原物质的情况下,可以使致敏程度减弱。
The re-sensitization caused by repeated multiple-seeding of Brucella 104-M viable vaccine resulted in the observation that seven (8) years after the vaccine had ceased vaccination, all of the eight patients had systemic myelo-reactivity Aggravating and developing trend, complement fixation test also remains positive, and there are symptoms of chronic brucellosis. Obviously, the systemic immunosensorial response of both the cellular and the humoral immunity resulting from multiple antigen stimulation by Brucella antigens is an immune disease that deserves our attention and attention. In the case of continuing processing of animal products and exposure to corresponding antigenic substances, most allergens appear to be sensitized to increased sensitization levels, and sensitization may be attenuated in the event of exposure to the corresponding antigenic substance.