论文部分内容阅读
应用放射免疫测定法对兔同灶性脑出血和脑缺血性动物模型进行血清ＡＣＴＨ、皮质醇含量进行测定，研究了与脑组织病理改变的相关性，以探讨对Ｈ／Ｐ／Ａ功能紊乱的机制。脑出血与脑缺血模型急性期血清ＡＣＴＨ、皮质醇含量水平明显高于恢复期、假手术组及正常对照组，以脑出血模型组为明显。恢复期时脑缺血模型组Ｈ／Ｐ／Ａ功能恢复较差，提示Ｎ／Ｐ／Ａ功能紊乱程度与脑组织病理损害程度呈正相关。
Serum ACTH and cortisol levels were measured in rabbits with focal cerebral hemorrhage and cerebral ischemic animal models by radioimmunoassay. The correlations between the serum ACTH and cortisol levels in brain tissue were also studied. The effects of H / P / A disorder Mechanisms. The levels of serum ACTH and cortisol in acute phase of cerebral hemorrhage and cerebral ischemia model were significantly higher than those in recovery phase, sham operation group and normal control group. H / P / A function recovered poorly in cerebral ischemia model group at convalescent phase, suggesting that the degree of N / P / A dysfunction is positively correlated with the degree of pathological damage in brain tissue.