脑膜炎球菌感染仍然是儿童和成人发病与死亡的一个原因。此病在发达国家和发展中国家至今仍有爆发,病死率为10～30%。近年来发病率有所增高,为此作者回顾研究了1985～1988年100例住院患儿的临床表现和预后。患儿的主要表现为发热、休克和紫癜。无皮疹者占29％。100例中55例有脑膜炎,其中6例初次腰穿时脑脊液(CSF)并无异常,但培养有致病菌生长。总病死率为 Meningococcal infection remains a cause of morbidity and mortality in both children and adults. The disease is still outbreaks in developed and developing countries, the mortality rate was 10 to 30%. In recent years, the incidence has increased, for which the author reviewed the 1985 to 1988, 100 cases of hospitalized children with clinical manifestations and prognosis. The main manifestations of children with fever, shock and purpura. No rash accounted for 29%. Among 100 cases, 55 cases had meningitis, of which 6 cases had no abnormality of cerebrospinal fluid (CSF) during the initial lumbar puncture, but the growth of pathogenic bacteria was cultured. Total fatality rate is