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报告２５例癫痫患者在进行手术治疗时，皮层脑电监测下，取棘波最明显最多的大脑皮层做电镜观察，同时对８例病人的胼胝体也做电镜观察。结果发现超微结构下的神经细胞，突触与神经毡，星形胶质细胞，毛细血管及髓鞘均有不同程度的病理变化，突触前轴突末梢及突触后树突均发生不同程度的水肿，尤以突触后树突水肿明显并伴有突触前轴突末梢突触小泡的聚集增多。这些同癫痫的发生有密切关系，在癫痫发病和脑电棘波形成中具有重要意义，本文对这些改变进行分析讨论。
Report of 25 cases of epilepsy patients undergoing surgical treatment, cortical EEG monitoring, take the most obvious cortex in the encephalon observed by electron microscopy, and 8 cases of the corpus callosum electron microscopy. The results showed that ultrastructure of nerve cells, synapses and nerve felts, astrocytes, capillaries and myelin sheath have varying degrees of pathological changes, pre-synaptic axon terminals and postsynaptic dendrites are different Degree of edema, especially in the post-synaptic dendritic edema was accompanied by an obvious increase in synaptic vesicles at the presynaptic axon. These are closely related to the occurrence of epilepsy, and are of great significance in the pathogenesis of epilepsy and the formation of EEG waves. In this paper, we analyze and discuss these changes.