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目的：比较米非司酮配伍卡前列甲酯与米非司酮配伍米索前列醇终止早期妊娠的疗效。方法：妊娠≤４９ｄ孕妇１９９例，年龄２６±５ａ，随机分Ａ组８９例，Ｂ组１１０例。２组均用米非司酮２５ｍｇ，ｂｉｄ，３ｄ，于ｄ４，Ａ组阴道后穹窿置卡前列甲酯栓１ｍｇ。Ｂ组米索前列醇ｐｏ，６００μｇ。结果：Ａ和Ｂ组完全流产率各为８３％和９３．６％，经Ｘ２检验，Ｐ＜０．０５；胎囊排出时间，Ａ组４±５ｈ，Ｂ组３±６ｈ，２组无显著差异。结论：米非司酮配伍米索前列醇的抗早孕效果优于配伍卡前列甲酯。
OBJECTIVE: To compare the efficacy of mifepristone with cardiopulmonary bypass and mifepristone in combination with misoprostol to terminate early pregnancy. Methods: 199 pregnant women ≤ 49 days of pregnancy, age 26 ± 5a, randomly divided into group A 89 cases, group B 110 cases. 2 groups were treated with mifepristone 25mg, bid, 3d, in d4, A group of vaginal posterior fornix card front methyl ester suppository 1mg. Group B misoprostol po, 600μg. Results: The complete abortion rates in group A and group B were 83% and 93.6%, respectively, and the difference was statistically significant (P <0.05) by X2 test. The time to fetal sac exit was 4 ± 5 h in group A and 3 ± 6 h in group B, difference. Conclusion: The anti-pregnancy effect of mifepristone combined with misoprostol is better than that of kappa-methyl.