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SV40Tag(Tantigen)是一种肿瘤相关抗原,大约60%的人类肿瘤细胞中携带SV40基因,可与某些抑癌基因p53和Rb结合,刺激和促进癌细胞的生长。不少学者致力于研究诱导体内的SV40Tag特异性抗肿瘤免疫,包括促进SV40Tag呈递或构建重...
SV40Tag (Tantigen) is a tumor-associated antigen. About 60% of human tumor cells carry the SV40 gene and can bind to certain tumor suppressor genes p53 and Rb to stimulate and promote the growth of cancer cells. Many scholars have devoted themselves to studying the induction of SV40Tag-specific anti-tumor immunity in vivo, including the promotion of SV40Tag presentation or the construction of heavy...