盐酸喘通为一新型平喘药,毒性低,吸收良好,但因其排泄较快,需增加服药次数,故一些副作用相应增加。本文介绍了作者在研究制备琥珀酸喘通和双羟萘酸喘通并进行药理试验后证明两者抗组织胺的作用均较缓和而持久。如以适当比例制成长效制剂(前者为速释部分、后者为缓释部分),能够增强疗效,减轻副作用。 Hydrochloric acid asthma is a new type of antiasthmatic drugs, low toxicity, good absorption, but because of its excretion faster, the need to increase the number of medication, so a corresponding increase in some side effects. This article describes the author in the study of preparation of succinate and pamoate asthma and pharmacological tests showed that the two antihistamine role are more moderate and lasting. If made in a suitable ratio of the long-acting preparation (the former part for the immediate release, the latter for the slow release part), can enhance the efficacy and reduce side effects.