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本文总结胃癌患者外周血淋巴细胞微核测定的结果:在47例胃癌患者中共观察淋巴细胞47,000个,检出具有微核的淋巴细胞304个,平均微核出现率6.47‰,其分布在3—10‰之间,阳性率为91.4％;正常人102例,非吸烟组91例,共观察淋巴细胞91,000个,检出具有微核的淋巴细胞135个,其分布在0—6‰之间,阳性率1.1％,吸烟组11例,共观察淋巴细胞11,000个,检出具有微核的淋巴细胞49个,分布在2—6‰之间,阳性率9.1％。以非吸烟组、吸烟组分别与胃癌患者作对照差异显著(P<0.01)。
This article summarizes the results of micronucleus determination of peripheral blood lymphocytes in patients with gastric cancer: In 47 patients with gastric cancer, 47,000 lymphocytes were observed, and 304 micronuclei-associated lymphocytes were detected with an average micronucleus frequency of 6.47 ‰, which was distributed in 3— Between 10 days, the positive rate was 91.4%; 102 normal subjects and 91 non-smoking subjects. 91,000 lymphocytes were observed, and 135 micronuclei-associated lymphocytes were detected, ranging from 0 to 6 inches. The positive rate was 1.1%. In the smoking group, there were 11 cases. A total of 11,000 lymphocytes were observed. 49 lymphocytes with micronuclei were detected and distributed between 2 and 6 plaques. The positive rate was 9.1%. The difference between the non-smoking group and the smoking group was significantly different from that of the gastric cancer patients (P<0.01).