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目的研究老年2型糖尿病应用甘精胰岛素联合格列美脲方案治疗的优势。方法将本院2015年1月—2017年2月老年2型糖尿病患者90例随机分2组,每组45例,对照组应用诺和灵50R联合格列美脲治疗;实验组应用甘精胰岛素联合格列美脲方案治疗。2组患者血糖恢复正常时间和2型糖尿病治疗有效率、不良反应发生率进行比较,并比较治疗前后血糖水平。结果实验组2型糖尿病治疗有效率明显高于对照组(P<0.05)。实验组不良反应发生率明显低于对照组(P<0.05)。实验组患者血糖恢复正常时间短于对照组(P<0.05)。干预前2组血糖水平接近(P>0.05);干预后实验组血糖水平优于对照组(P<0.05)。结论老年2型糖尿病应用甘精胰岛素联合格列美脲方案治疗具有疗效确切、起效快和安全性高等优势,是老年2型糖尿病患者理想治疗方案,值得推广。
Objective To study the advantages of insulin glargine and glimepiride regimen in elderly type 2 diabetes mellitus. Methods From January 2015 to February 2017, 90 elderly patients with type 2 diabetes mellitus were randomly divided into two groups (n = 45 in each group). The control group was treated with noradrenate 50R plus glimepiride. The experimental group was given insulin glargine Treatment with glimepiride regimen. Two groups of patients with normal blood glucose recovery and type 2 diabetes treatment efficiency, the incidence of adverse reactions were compared and compared before and after treatment of blood glucose levels. Results The effective rate of type 2 diabetes in experimental group was significantly higher than that in control group (P <0.05). The incidence of adverse reactions in the experimental group was significantly lower than that in the control group (P <0.05). Patients in the experimental group had shorter recovery time than those in the control group (P <0.05). The levels of blood glucose were similar in the two groups before intervention (P> 0.05). The levels of blood glucose in the experimental group were better than those in the control group after intervention (P <0.05). Conclusion The treatment of senile type 2 diabetes with glargine and glimepiride has the advantages of good curative effect, quick onset and high safety. It is an ideal treatment for elderly type 2 diabetic patients and is worth promoting.