用联合化疗治疗晚期乳腺癌已有20余年了。在这期间,许多试验证明,联合化疗比单剂化疗有更高的疗效。本文报导了东部肿瘤研究组与西部肿瘤研究组关于222例进展性乳腺癌化疗的总结。两组均采用5-氟脲嘧啶、环磷酰胺、氨甲喋呤及强的松治疗,此外,东部治疗组加用长春新碱,而西部治疗组加用三碘甲状腺氨 The use of combination chemotherapy for advanced breast cancer has been more than 20 years. During this period, many trials have demonstrated that combination chemotherapy has a higher efficacy than single-agent chemotherapy. This article reports the conclusions of 222 cases of advanced breast cancer chemotherapy by the Eastern Cancer Research Group and the Western Cancer Research Group. Both groups were treated with 5-fluorouracil, cyclophosphamide, methotrexate and prednisone. In addition, the eastern treatment group was treated with vincristine, while the western treatment group was treated with triiodothyronine.