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临床上常用的莨菪类药物有阿托品、东莨菪碱、山莨菪碱和障柳碱,这组药物均可从莨菪属植物中提取,人工业已合成,后两种是我国首先分离,并应用于临床。莨菪类药物对受体的作用莨菪类药物对乙酰胆碱(Ach)能的作用 1.Ach能的分布。从生物个体发生学来看。Ach能是最早的神经介质,在身体分布很广。Ach能受体分M、N二种。①中枢分布:感觉和运动信息传递最后的神经元全系Ach能神经,此外,脑干走向皮层的上行非特异投射系统以及大脑皮层内部和边缘系统内部的联络神经元也有一部分属于Ach能神
Clinically commonly used drugs are atropine, scopolamine, anisodamine and dysbicailine, this group of drugs can be extracted from the genus Hsia, Artificial synthesis has been made, the latter two are China’s first separation, and used in clinical. The role of the herbivore on the receptor The effect of the herbivore on the acetylcholine (Ach) energy 1. The distribution of Ach energy. From the biology of individual genetics point of view. Ach is the earliest neurotransmitter, widely distributed in the body. Ach receptors can be divided into M, N two kinds. ① central distribution: the sensory and motor information transmission of the entire nervous system Ach nerve, in addition, the brain stem to the cortex of the upstream non-specific projection system and the cerebral cortex of the internal and limbic system of contact neurons also part of the Ach God