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目的:分析ST段抬高型心肌梗死择期介入治疗的心功能及心室重构改善的疗效。方法:选择2013年3月至2016年3月接诊的120例急性ST段抬高型心肌梗死(AMI)患者进行研究,根据患者入院后治疗方案的不同将其分为观察组和对照组。对照组患者入院后常规检测血清心肌酶及肌钙蛋白,均给予常规抗凝、抗血小板聚集、血管紧张素转换酶抑制剂、他汀类及硝酸酯类药物等治疗,并行溶栓治疗。观察组在常规的治疗基础上,择期行PCI治疗,用球囊预扩张后均置入冠状动脉内支架。并通过超声心动图检查患者的恢复情况,跟踪记录患者的康复情况。结果:两组患者住院期间均接受常规β-受体阻滞剂、抗血小板聚集、血管紧张素转换酶抑制剂、他汀类及硝酸酯类药物等药物治疗,两组患者使用药物情况无显著性差异(P>0.05);对比对照组和观察组治疗前后心脏功能参数的变化,可知两种治疗方案对心肌梗死患者均有疗效,但观察组择期PCI治疗后左室舒张末径(47.4±1.8mm)明显小于对照组(47.9±1.6mm);观察组的左心室射血分数(54.6±7.1%)明显高于对照组(51.7±6.5%)。根据长期的跟踪治疗,观察组心肌梗死的显效率(88.3%)明显高于对照组的显效率(73.3%),可见心肌梗死患者择期介入治疗的康复效果明显高于常规方案的效果,两组数据具有可比性(P<0.05)。结论:ST段抬高型心肌梗死患者择期介入治疗的效果明显高于常规药物治疗,并进一步改善心脏功能。
Objective: To analyze the cardiac function and ventricular remodeling in patients with ST-elevation myocardial infarction undergoing elective interventional therapy. Methods: A total of 120 patients with acute ST-segment elevation myocardial infarction (AMI) admitted from March 2013 to March 2016 were enrolled in this study. Patients were divided into observation group and control group according to different treatment options after admission. Patients in the control group were routinely tested for serum myocardial enzymes and troponin after admission, and were given routine anticoagulation, antiplatelet aggregation, angiotensin converting enzyme inhibitors, statins and nitrates and thrombolytic therapy. On the basis of routine treatment, the observation group underwent elective PCI, and the stent was placed in the coronary artery after balloon dilation. And by echocardiography to examine the recovery of patients, tracking the patient’s recovery record. Results: During the hospitalization, both groups received conventional β-blockers, antiplatelet aggregation, angiotensin converting enzyme inhibitors, statins and nitrates and other drugs, the two groups of patients with no significant drug use (P> 0.05). Comparing the changes of cardiac function parameters between the control group and the observation group before and after treatment, we can see that the two treatment regimens are effective in patients with myocardial infarction, but the left ventricular end-diastolic diameter (47.4 ± 1.8) mm) was significantly lower than that of the control group (47.9 ± 1.6mm). The left ventricular ejection fraction (54.6 ± 7.1%) in the observation group was significantly higher than that of the control group (51.7 ± 6.5%). According to the long-term follow-up treatment, the markedly effective rate of myocardial infarction in observation group (88.3%) was significantly higher than that of control group (73.3%). The recovery effect of elective interventional therapy in patients with myocardial infarction was significantly higher than that of conventional regimen. The data is comparable (P <0.05). Conclusion: The effect of elective interventional therapy in patients with ST-elevation myocardial infarction is significantly higher than that of conventional drug treatment and further improve cardiac function.