已有报告指出较高剂量的噻嗪类利尿利可能引起室性心律失常.作者采取随机双盲交叉实验法,观察了推荐的小剂量双氢克尿塞(50毫克/日)对老年人室性心律失常的影响.因高血压、心衰或浮肿等原因服用利尿剂的患者37例、年龄≥65岁、双氢克尿塞的剂量为50毫克/日,服用该药或安慰剂的时间均为6周.实验开始前检查血钾及心电图,服药满6周后进行24小时的心电监测、复查血钾.出现室早>30个/小时;成对室早或 It has been reported that higher doses of thiazide diuretic may cause ventricular arrhythmias. The authors used a randomized double-blind crossover test to observe the effects of the recommended low-dose hydrochlorothiazide (50 mg / day) on ventricular arrhythmias in the elderly 37 cases of patients taking diuretics due to high blood pressure, heart failure or edema, age ≥ 65 years, hydrochlorothiazide dose of 50 mg / day, taking this drug or placebo for 6 weeks before the start of the experiment Check serum potassium and ECG, medication for 6 weeks after 24 hours of ECG monitoring, review of potassium. Appear room as early as 30 / hour; Paired room early or