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检测对象均为儿童,T-细胞型急性淋巴细胞白血病(ALL)17例、普通型ALL 22例、T-细胞型淋巴瘤3例和对照组14例.以血清硫巴比土酸(TBA)反应测定脂质过氧化产物.T-细胞型ALL的TBA反应显著高于其余组(P<0.01),且与外周血白细胞数呈正相关(r=+0.59).以放射免疫法测定前列腺素E_2(PGE_2).T-细胞型ALL的PGE_2升高并与TBA反应呈正相关(r=+0.84),7例被检者有5例大于对照组?+2SD,
All subjects were children, including 17 cases of T-cell acute lymphoblastic leukemia (ALL), 22 cases of normal ALL, 3 cases of T-cell lymphoma, and 14 cases of control group. Serum thiabarbituric acid (TBA) The TBA response to lipid peroxidation product and T-cell ALL was significantly higher than that in other groups (P<0.01), and was positively correlated with the number of white blood cells in peripheral blood (r=+0.59). Prostaglandin E2 was measured by radioimmunoassay. (PGE 2). PGE 2 in T-cell ALL was increased and positively correlated with TBA response (r=+0.84). In 7 patients, 5 patients were greater than control group +2 SD.