脉络宁是由石斛、玄参、牛膝等制成的新型中药制剂。随着应用的日益广泛,不良反应时有报道,现加以总结,以引起临床医师和药师的注意。 1 皮肤过敏 主要表现:全身皮肤瘙痒,出现散在红色斑丘疹或充血性皮疹,输液部位红、肿、热等,一般予以抗过敏治疗,症状逐渐缓解。文献报道2例患者在静脉点滴脉络宁后,出现全身皮肤瘙痒,其中1例于输液部位出现红肿,边界不清,为弥漫性红肿。另1例胸部出现散在点状充血性皮疹,遂停用脉络宁,口服扑尔敏,症状得以缓解。 2 过敏性休克 于忠国,王燕报道1例脑外伤患者,9岁,静脉点滴脉络宁10 min后,突然出现胸闷、憋气、头晕、恶心、面色苍白、口唇紫绀、肢端发凉、脉搏细速,血压8kPa/4kPa,考虑为过敏性休克。停输脉络宁,给予地塞米松5mg,10min后患者面色渐红润,脉搏有力,肢体转暖,血压升至11kPa/6kPa。林雪报道1高血压患者,静脉点滴脉络宁数分钟即感胸 Mailuoning is a new type of traditional Chinese medicine made of Dendrobium, Scrophulariaceae, Achyranthes. With the increasingly wide range of applications, there are reports of adverse reactions, are summarized, to attract the attention of clinicians and pharmacists. 1 skin allergy The main manifestations: systemic skin itching, scattered red rash or congestive rash, infusion site red, swollen, hot, etc., generally be anti-allergy treatment, symptoms gradually eased. Reported in the literature 2 patients intravenous Mailuoning appear systemic pruritus, including 1 case of infusion site inflamed, unclear boundary, diffuse redness. Another case of chest appeared scattered spot congestive rash, then stop Mailuoning, oral chlorpheniramine, symptoms can be alleviated. 2 anaphylactic shock in Zhongguo, Wang Yan reported 1 case of traumatic brain injury, 9 years old, intravenous Mailuoning 10 min, the sudden onset of chest tightness, suffocation, dizziness, nausea, pale, blue lips, cold extremities, pulse fine Speed, blood pressure 8kPa / 4kPa, considered as anaphylactic shock. Stop meridian Ning, given dexamethasone 5mg, 10min after the patient gradually rosy face, strong pulse, limb warming, blood pressure rose to 11kPa / 6kPa. Lin Xue reported 1 hypertensive patients, intravenous drip Mailuoning Ning sense of the chest a few minutes