论文部分内容阅读
目的分析轻、中度老年慢性阻塞性肺疾病(COPD)患者肺功能改变与肺动脉压力、心脏结构和功能变化特点及相关性。方法选取2008年8月-2010年12月于该院干疗科确诊的轻、中度老年COPD稳定期患者52例,分析轻、中度老年COPD患者肺功能改变与肺动脉压力、心脏结构和功能变化特点及相关性。结果轻、中度老年COPD患者Pa O2逐渐降低;轻、中度老年COPD均有弥散功能逐渐下降;轻、中度老年COPD患者PASP逐渐升高;轻、中度老年COPD患者Pa O2、FEV1%、FEV1/FVC与PASP呈负相关(P<0.05)。结论轻、中度老年COPD患者心腔大小变化不明显,左心功能未受影响;轻、中度老年COPD患者的肺动脉收缩压增高与低氧、肺功能的损害程度有关。
Objective To analyze the changes of pulmonary function and the changes of pulmonary artery pressure, cardiac structure and function in patients with mild or moderate chronic obstructive pulmonary disease (COPD) and their correlation. Methods Totally 52 elderly patients with mild and moderate chronic obstructive pulmonary disease (COPD) diagnosed in the department of orthopedics in our hospital from August 2008 to December 2010 were enrolled in this study. The changes of pulmonary function, pulmonary arterial pressure, cardiac structure and function Change characteristics and relevance. Results PaO2 of mild and moderate COPD patients decreased gradually. The diffuse function of mild and moderate COPD patients gradually decreased. The PASP of mild and moderate COPD patients increased gradually. PaO2, FEV1% , FEV1 / FVC was negatively correlated with PASP (P <0.05). Conclusions There is no obvious change in the size of the heart cavity in mild and moderate COPD patients and left ventricular function is not affected. Increased pulmonary artery systolic pressure in mild and moderate COPD patients is related to the severity of hypoxia and pulmonary function.