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目的:探讨经尿道前列腺电切术(TURP)与等离子体双极前列腺电切术(PKRP)治疗高危Ⅲ°前列腺增生(BPH)的有效性和安全性。方法:回顾性分析我院2010年12月至2013年12月收治的高危Ⅲ°前列腺增生患者66例,分别采用TURP(单极组)和PKRP(双极组)治疗,比较两组患者手术前后国际前列腺症状评分(IPSS)、生活质量评分(QOL)、残余尿量(RUV)、电解质、手术时间和术中失血量、手术并发症等指标的变化。结果:两组患者年龄、前列腺体积、术前IPSS、QOL、RUV等指标均无统计学差异(P>0.05)。两组患者治疗后IPSS、QOL、RUV均明显改善,与治疗前比较差异显著(P<0.05),但两组间比较无统计学差异(P>0.05)。单极组术后血Na+较术前降低(P<0.05),而双极组手术前后血Na+水平未见明显变化。单极组术后血糖较术前升高(P<0.05),而双极组手术前后血糖水平未见明显变化。单极组术中出血量较双极组高(P<0.05)。结论:PKRP与TURP治疗高危Ⅲ°前列腺增生患者均有良好疗效,其中PKRP对患者血Na+、血糖的影响及术中出血及术后并发症明显小于TURP,具有良好的安全性。
Objective: To investigate the efficacy and safety of transurethral resection of the prostate (TURP) and plasma bipolar prostate resection (PKRP) in the treatment of high-risk benign prostatic hyperplasia (BPH). Methods: A retrospective analysis of 66 patients with benign prostatic hyperplasia in our hospital from December 2010 to December 2013 were retrospectively analyzed. TURP (unipolar group) and PKRP (bipolar group) International Prostate Symptom Score (IPSS), Quality of Life Score (QOL), Residual Urine Volume (RUV), Electrolyte, operation time and intraoperative blood loss, surgical complications and other indicators. Results: The age, prostate volume, preoperative IPSS, QOL, RUV and other indexes had no significant difference between the two groups (P> 0.05). The IPSS, QOL and RUV of both groups were significantly improved after treatment (P <0.05), but there was no significant difference between the two groups (P> 0.05). Na + level in monopolar group was lower than that before operation (P <0.05), while there was no significant change in blood Na + level in bipolar group before and after operation. Blood glucose in unipolar group was significantly higher than that before operation (P <0.05), while no significant changes were found in blood glucose level before and after bipolar surgery. Blood loss in unipolar group was higher than bipolar group (P <0.05). CONCLUSION: Both PKRP and TURP have a good curative effect in patients with benign prostatic hyperplasia who have Ⅲ ° degree of benign prostatic hyperplasia. The effect of PKRP on blood Na +, blood glucose, intraoperative bleeding and postoperative complications is less than TURP, which has good safety.