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本文应用胶原、网状和弹力纤维三联染色法，对于７６例不同类型的肺癌病例做了特殊染色，观察其纤维增生的类型、分布规律以及存在的意义。结果表明：①弹力纤维和网状纤维的增生，是机体对肺癌的一种防御性反应，可以做为综合判断患者预后的指标之一，而胶原纤维增生对肺癌的反应不敏感。②纤维组织增生程度与肺癌组织学类型无明显关系，而与肿瘤细胞分化程度密切相关。③三联染色法能够在镜下同时观察到弹力、网状和胶原３种纤维，染色效果较好，可以在病理诊断和研究中应用。
In this paper, special staining was performed on 76 cases of different types of lung cancer using the triple staining method of collagen, mesh and elastic fibers. The type, distribution and significance of fibrosis were observed. The results showed that: 1 The proliferation of elastic fibers and reticular fibers is a defensive reaction of the body to lung cancer and can be used as an index to comprehensively judge the prognosis of patients. Collagen fibrosis is not sensitive to lung cancer. 2 The degree of fibrous tissue proliferation was not significantly related to the histological type of lung cancer, but closely related to the degree of tumor cell differentiation. 3The tri-staining method can observe three kinds of fibers of elasticity, reticulation and collagen at the same time under the microscope. The dyeing effect is better and can be applied in pathological diagnosis and research.