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目的:探讨运用调强放疗和影像引导下的放疗技术进行乳腺癌椎体转移剂量提升治疗的临床价值。方法:乳腺癌椎体转移患者11例,在相同脊髓耐受剂量和保证常规适形放疗治疗剂量基础上,接受调强放疗和影像引导下的放疗,提高放疗剂量,观察治疗效果及不良反应。结果:调强放疗和影像引导下的放疗技术可提高椎体病灶治疗剂量约20%,短期临床疗效较好,无明显不良反应。结论:调强放疗和影像引导下的放疗技术可提高肿瘤病灶局部治疗剂量,更好地保护正常组织,提高患者生存质量。
Objective: To investigate the clinical value of intensity-modulated radiotherapy and radiotherapy-guided radiotherapy in the treatment of breast cancer with vertebral body mass transfer. Methods: Eleven patients with vertebral metastases of breast cancer received radiotherapy under intensity modulated radiotherapy and imaging guided by the same spinal cord tolerance dose and the dose of conventional conformal radiotherapy. The dose of radiotherapy was increased to observe the therapeutic effect and adverse reaction. Results: IMRT and radiotherapy-guided radiotherapy can improve the therapeutic dose of vertebral body lesions by about 20%. The short-term clinical efficacy is better and no obvious adverse reactions are found. Conclusion: IMRT and radiotherapy-guided radiotherapy can improve the local treatment dose of tumor lesions, protect the normal tissue better and improve the quality of life of patients.