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目的 :了解老年慢性阻塞性肺疾病 (COPD)患者的瘦素与营养状态的关系 ,探讨 COPD营养不良的机制。方法 :对32例 COPD患者 (分为营养不良组 17例 ,非营养不良 15例 )和 15例健康老年人进行营养状态评价 ,同时测定其血清瘦素水平。结果 :(1) COPD营养不良组的瘦素 (1.5 6± 1.0 ) μg/L 低于非营养不良组 (5 .33± 3.5 6 ) μg/L 和健康对照组 (5 .2 4± 3.4 5 ) μg/L。(2 )各组瘦素水平与各营养指标均呈显著相关性。结论 :瘦素浓度与 COPD营养不良有关
Objective: To understand the relationship between leptin and nutritional status in elderly patients with chronic obstructive pulmonary disease (COPD) and to explore the mechanism of malnutrition in COPD. Methods: The nutritional status of 32 COPD patients (17 cases of malnutrition, 15 cases of non-malnutrition) and 15 healthy controls were evaluated. Serum leptin level was also measured. Results: (1) The levels of leptin (1.56 ± 1.0) μg / L in the malnourished COPD group were significantly lower than those in the non-malnourished group (5.33 ± 3.56) μg / L and the healthy controls ) μg / L. (2) The levels of leptin in each group were significantly correlated with the nutrition indexes. Conclusion: Leptin concentration is associated with malnutrition in COPD