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目的观察琥珀酸美托洛尔缓释片在扩张性心肌病患者的应用效果。方法 26例患者在常规治疗基础上加用琥珀酸美托洛尔缓释片,每天一次,共6个月,观察患者治疗前后心肌耗氧指数、LVEDD、LVEF和6MWD变化情况。结果治疗后患者LVEDD、心肌耗氧指数均明显下降,而LVEF和6MWD均明显提高,各指标治疗前后比较P<0.05。结论琥珀酸美托洛尔缓释片治疗扩张型心肌病效果显著,服用方便。
Objective To observe the effect of metoprolol succinate sustained-release tablets in patients with dilated cardiomyopathy. Methods Twenty - six patients received metoprolol succinate sustained - release tablets on a routine basis for 6 months. The changes of myocardial oxygen consumption index, LVEDD, LVEF and 6MWD before and after treatment were observed. Results After treatment, LVEDD and myocardial oxygen consumption index decreased significantly, while LVEF and 6MWD were significantly increased, P <0.05 before and after treatment. Conclusion metoprolol succinate sustained-release tablets for the treatment of dilated cardiomyopathy significant effect, easy to take.