视网膜母细胞瘤(RB)是小孩最常见的眼内肿瘤。在总人口中,是第二种最常见的眼内肿瘤。双眼发病占25～30％。据说在西欧,这种肿瘤的发病率有稳步上升情况,出生婴儿患本病的,在1931年为1:34,000,在1961年为1:14,000。本病增加的原因可能是多方面的,患者被治愈,再生子女,以致患病的人数上升,此外诊断技术的进步,或者还有其他未知的原因,致使本病有增多的趋势。近年来,RB的治疗及预后有很大进步,死亡率少于15％。一般认为,RB的旱期诊断与治疗,眼球的保存率与病人的 Retinoblastoma (RB) is the most common intraocular tumor in children. In the total population, it is the second most common intraocular tumor. Occurrence of binocular accounts for 25 to 30%. It is said that in Western Europe, the incidence of this type of cancer has steadily increased. The number of babies born to this disease was 1:34,000 in 1931 and 1:14,000 in 1961. The reasons for the increase in the disease may be many, the patient was cured, the reproduction of children, so that the number of patients increased, in addition to advances in diagnostic technology, or there are other unknown reasons, resulting in the trend of the disease has increased. In recent years, the treatment and prognosis of RB have made great progress, with a mortality rate of less than 15%. Generally believed that the diagnosis and treatment of RB in dry period, the preservation rate of the eyeball and the patient