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目的了解粪中日本血吸虫卵计量变异特征.方法对清溪二村民连续7次收集粪便,用改良Kato法涂片2张;对44倒粪检阳性者,再涂片10张.结果一村粪检累计检出率从单次42.38％增加到7次的68.26％,二村从17.02增加到35.98％.虫卵在同一粪便中的分布并非完全随机.结论改良Kato法的敏感性与人群感染度及粪便取样部位有关;个体内虫卵计量变异,可用负二项分布来描述其特征.“,”Aim For studying variations of faceal S. japonicum egg counts. Methods Population stool examinations were collected with duplicate standard 41. 5mg Kato-Katz thick smears on 7 consecutive days in Zhuxi village. In order to observe variations within a stool 10 repeated egg counts from 44 individuals and egg counts from 5 individuals, 3 days, and 15 locations in the stool (5 sections and 3 deepths) were conducted. Results The proportion of indivaduals with at least one positive count rose from 42. 38 % after a single measurement to 68. 82% after 7 measurements in village Ⅰ, and in village Ⅱ from 17. 02% to 35. 98%, respectively. Within a stool, egg counts decrease significantly from the beginning of the stool to the end, and the outside layer to centre. Conclusions The sensitivity of Kato method largely depends on intensity of population and locations of a stool specimen. Intraindividual egg counts variation can be descibed by a negative binomial distribution.