The previous experiments of wire drawing with ultrasonic vibration were mostly carried out on self-made machine or drawing test machine and the drawing speed didn’t conform to practical production. In order to promote the practical application of the technology, the ultrasonic vibration system was designed and manufactured by using the classical dynamics method. The dynamic characteristic of the ultrasonic vibration system was analyzed. The performance parameters of the system were measured on the resistance analyzer. The oxygen-free brass wire drawing with ultrasonic vibration at the approximate speed of practice was carried out on the LH-200/17 drawing machine. By comparing the wire drawing through ultrasonic vibration and the conventional wire drawing, the experimental results show that the drawing process with ultrasound was steady at the high drawing speed of 1 126 mm/s, while the broken wire often occurs at the speed of 980 mm/s during the conventional wire drawing; the ultrasonic vibration reduced the drawing force by 7 %; and the ultrasound also reduced the uneven deformation of the wire and greatly improved the surface quality of the wire. The research results provide theoretical and experimental support for the practice and application of the wire drawing by ultrasonic vibration.