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近年玻璃体手术的兴起和普及,使人们对手术眼内的置换材料产生了极大的兴趣,不论是灌注液体、气体、还是粘性物质,都应以维持视网膜、睫状体、晶体和角膜的结构和功能为目的,而不局限于一种组织的保全或机械的充填。至于玻璃体手术后玻璃体的粘滞性显著下降,是玻璃体构造和机能损伤的一种表现,它反映了透明质酸的分解。Pruetter(1979)总结266例玻璃体腔注入透明质酸的患者,证明人眼可以很好地耐受。但大部分病例4～8天后才能看清眼底。术后玻璃体腔混浊和血浆样房水的形成与透明质酸的使用直接有关,虽事先使用激素和水杨酸亦不能防止。而血管通透性的增加可长达3个月之久。故一般认为透明质酸的术后反应大于生理盐水(NS)。
The rise and popularization of vitreous surgery in recent years has led to great interest in the replacement of surgical materials in the eye. Whether perfusion of liquid, gas, or viscous substances, the structure of the retina, ciliary body, crystal and cornea should be maintained And function for the purpose, not limited to a tissue preservation or mechanical filling. As for the vitreous body after vitreoretinal viscosity decreased significantly, is a manifestation of vitreous structure and function damage, which reflects the decomposition of hyaluronic acid. Pruetter (1979) concluded that 266 eyes of patients with hyaluronic acid injected into the vitreous cavity were shown to be well tolerated by the human eye. However, most cases 4 to 8 days to see the fundus. Postoperative vitreous opacity and the formation of plasma-like aqueous humor and the use of hyaluronic acid directly related, although the use of hormones and salicylic acid can not be prevented. The increase in vascular permeability can be as long as 3 months. It is generally believed that hyaluronic acid postoperative response than saline (NS).