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目的观察复方α酮酸联合尿毒清对维持性血液透析患者营养状况的影响。方法将80例长期血液透析患者随机分为观察组和对照组各40例。在常规透析基础上,对照组给予低蛋白饮食,观察组在低蛋白饮食基础上加用复方α酮酸联合尿毒清治疗。分别在治疗前及治疗6个月后检测2组患者的体质量指数(BMI)、血清白蛋白(Alb)、血红蛋白(Hb)、胆固醇(TC)及三酰甘油(TG)水平。结果治疗前2组患者观察指标水平比较差异无统计学意义(P>0.05)。治疗6月后,观察组患者BMI、Alb、Hb水平均高于治疗前和对照组,TC、TG水平均低于治疗前和对照组,差异均有统计学意义(P<0.05)。结论复方α酮酸联合尿毒清可有效改善维持性血透患者的营养状况,提高患者的生存质量。
Objective To observe the effects of compound α-ketoacid combined with nourishing serum on the nutritional status of maintenance hemodialysis patients. Methods 80 cases of long-term hemodialysis patients were randomly divided into observation group and control group, 40 cases each. On the basis of routine dialysis, the control group was given a low-protein diet, the observation group in combination with low-protein diet plus compound α-keto acid combined with niacin treatment. Body mass index (BMI), serum albumin (Alb), hemoglobin (Hb), cholesterol (TC) and triglyceride (TG) were measured before treatment and 6 months after treatment. Results Before treatment, there was no significant difference between the two groups (P> 0.05). After 6 months of treatment, the levels of BMI, Alb and Hb in the observation group were higher than those before treatment and in the control group, and the TC and TG levels were lower than those before treatment and the control group (P <0.05). Conclusions Compound α-ketoacid combined with Niaoduqing can effectively improve the nutritional status of patients with maintenance hemodialysis and improve the quality of life of patients.