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目的探讨EnSite标测指导下射频消融治疗特发性右室流出道室性早搏的临床效果及对心肌损伤的影响。方法回顾性分析我院2013年1月至2016年1月收治的84例右室流出道室性早搏行射频消融手术治疗患者的临床资料,对比两组患者的手术效果。结果本组中50例患者在常规电生理标测指导下实施射频消融手术(常规组)、34例患者在EnSite标测指导下射频消融治疗(EnSite组)。EnSite组患者的标测时间、射频消融时间、X线曝光时间、手术时间均显著的低于常规组,差异具有统计学意义(P<0.05)。术前,EnSite组和常规组的室性早搏数量对比,差异不具有统计学意义(P>0.05);术后,EnSite组的24 h室性早搏数量显著低于常规组(P<0.05);术后72 h,EnSite组的CK、CKMB、c Tn T、AST、LDH、Mb、HBDH水平显著低于常规组(P<0.05)。结论 EnSite标测指导下射频消融治疗特发性右室流出道室性早搏能显著缩短操作时间、减轻对患者心肌造成的损伤,手术效果可靠。
Objective To investigate the clinical effect of radiofrequency ablation guided by EnSite mapping on idiopathic right ventricular outflow tract premature ventricular contractions and its effect on myocardial injury. Methods The clinical data of 84 patients with right ventricular outflow tract premature ventricular contractions treated by radiofrequency catheter ablation in our hospital from January 2013 to January 2016 were retrospectively analyzed. The operative effects were compared between the two groups. Results Fifty patients underwent radiofrequency ablation (routine group) under the guidance of conventional electrophysiological mapping and 34 patients underwent radiofrequency catheter ablation (EnSite group) guided by EnSite mapping. EnSite group of patients in the mapping time, radiofrequency ablation time, X-ray exposure time, operation time were significantly lower than the conventional group, the difference was statistically significant (P <0.05). Before surgery, there was no significant difference in the number of premature ventricular contractions in EnSite group and routine group (P> 0.05). After operation, the number of premature ventricular contractions 24 h in EnSite group was significantly lower than that in routine group (P <0.05). The levels of CK, CKMB, cTn T, AST, LDH, Mb and HBDH in EnSite group were significantly lower than those in the conventional group at 72 h after operation (P <0.05). Conclusion Under the guidance of EnSite mapping radiofrequency catheter ablation of premature right ventricular outflow tract premature ventricular contraction can significantly shorten the operation time and reduce myocardial damage caused by the patient, the operation effect is reliable.