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(179)有关移植物的(接受或排斥的)五个规律是什么? 答:1.同基因个体的移植物被接受; 2.同种异体的移植物被排斥; 3.纯系双亲给予杂交仔一代(F_1)的移植物被接受;杂交子一代给予双亲的移植物被排斥; 4.来自杂交二代(F_2)及其后裔的移植物能被F_1所接受; 5.来自杂交系亲本的移植物,能被某些F_2 接受,而被另一些F_2个体所排斥。 (180)已知的小鼠组织相容性位点有多少? 答:小鼠的主要组织相容性复合体(MHC=majorhistocompatibility Complex)在17号染色体上,其中至少含10~15个位点,其它次要组织相容性位点分散在1、2、4、5、7、8、9、11、15、19号及x,y染色体上。截至1979年,总共发现至少有40个组织相容性位点,即H-loci。已被证实,其中半数左右已在染色体上定位,
(179) What are the five laws (receiving or repelling) related to grafts? A. 1. Allogeneic transplants are accepted; 2. Allogeneic transplants are rejected; 3. Crosses are given by pure parents. Transplants from the young generation (F_1) were accepted; grafts given to the parents by the hybrid generation were rejected; 4. transplants from the second generation of hybrids (F_2) and their progeny could be accepted by F_1; 5. parents from the hybrids Grafts, which can be accepted by some F2s, are rejected by other F_2 individuals. (180) What is the known mouse histocompatibility site? Answer: The mouse’s major histocompatibility complex (MHC=majorhistocompatibility complex) is on chromosome 17, which contains at least 10 to 15 sites. The other minor histocompatibility sites are scattered on 1, 2, 4, 5, 7, 8, 9, 11, 15, 19 and x,y chromosomes. As of 1979, a total of at least 40 histocompatibility sites, H-loci, were discovered. It has been confirmed that about half of them have been located on chromosomes.